Detections of coronavirus (COVID-19) cases in England remained high in week 45 with a slight increase on the previous week.
Case rates have increased across all age groups. The highest case rates were seen in those aged 20 to 29, with a rate of 358.9 per 100,000 population.
The biggest increase was seen in those aged 80+ with a rate of 217.1 per 100,000 population in week 45, compared to 192.4 in the previous week.
Case rates per 100,000 were highest in the North East, North West and Yorkshire and the Humber.
Positivity rates through Pillar 1 (NHS and PHE testing) and Pillar 2 (community testing) have decreased slightly.
Positivity rates were highest among those aged 80 and over tested through Pillar 1 (NHS and PHE testing), as they are more likely to be in hospital, and in 10 to 19-year-olds tested through Pillar 2 (community testing).
COVID-19 hospital and critical care admission rates continued to increase.
The hospitalisation rate for COVID-19 was 14.03 per 100,000 in week 45 compared to 13.53 per 100,000 in the previous week.
By NHS regions, the highest hospital admission rates for COVID-19 were observed in the North East.
By age group, the highest hospital admission rates were in those aged 85 and over.